We'll review some of the likely topics asked on the boards.
Q: What is the BEST diagnostic test for detecting iron deficiency anemia?
A: Serum Ferritin level... (serum iron test is mainly for screening)
Q: What physical SIGNS are highly specific for iron deficiency anemia?
A: Both.... Blue Sclera and Koilonychia...(spoon shaped fingernails)
Q: What infectious agent can cause sudden Aplastic Anemia in a young adult?
A: Parvovirus-B19 infection
Q: What disorder is the most common cause of vitamin B12 deficiency?
A: Pernicious Anemia... (due lack of gastric intrinsic factor)
Q: What peripheral smear finding is associated with Lead Poisoning?
A: Basophilic Stippling...(small granules in RBC's)
Q: What is the BEST test for definitive diagnosis of vitamin B12 deficiency?
A: Serum Methylmalonic Acid...( serum B12 level used mainly for screening).
Q: What is the MOST frequent blood transfusion reaction?
A: FNHTR (Febrile Non-Hemolytic Transfusion Reaction). Use Leukocyte reduced RBC's.
Q: Which type of anemia presents with paresthesias/ataxia/prominent NEURO symptoms?
A: Cyanocobalamin deficiency(B12). Causes demyelination of the dorsolateral portion
of the spinal cord. Foot burning...numbness are often the FIRST symptoms.
Q: Does deficiency of Folic Acid alone cause neurologic abnormalities?
A: No....only B12 deficiency.
More topics soon to follow...
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