Tuesday, December 8, 2009

CARCINOMA ASSOCIATED SYNDROMES

Often asked, will be questions related directly or indirectly to malignant
disorders. Of those, we'll list the most common ones...likely to show-up
on your boards...



Q: HYPONATREMIA is commonly associated with which malignancy?


A: SMALL CELL CARCINOMA of the LUNG. (An easy way to memorize this
is the remember the letter "S"......"S"mall cell carcinoma causes "S"IADH
which leads to a change in "S"odium. (Hyponatremia).
*****Also of importance, SIADH only causes Hyponatremia!!!



Q: What is the most common PARANEOPLASTIC SYNDROME?

A: HYPERCALCEMIA ....especially common in Multiple Myeloma, Metastatic
Breast cancer and Squamus Cell Carcinoma of the Lung.



Q: What is the most common cause of SUPERIOR VENA CAVA(SVC) SYNDROME?

A: SMALL CELL CARCINOMA of the LUNG. The CXR will show a widened mediastinum.



Q: H. PYLORI is a PRIMARY RISK FACTOR for which cancer?

A: GASTRIC CARCINOMA. It is also frequently the cause of MALT Lymphoma.



Q: Which CELL TYPE is the most common cause of TESTICULAR CANCER?

A: GERM CELL...will cause about 95% of the these cancers. They will ususally
cause elevated AFP and B-HCG levels.



We'll be back in a few days....study well!!!!

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